A new way to fight antibiotic resistance (2026)

The battle against antibiotic resistance has taken an intriguing turn, and it's time to explore a potential game-changer. Antibiotic resistance, a growing threat to global health, has a new adversary, and it's a story that begins with a Scottish physician's serendipitous discovery in 1928.

Dr. Alexander Fleming's accidental encounter with penicillin revolutionized medicine, but it also sparked a complex issue: the rise of antibiotic resistance. Today, we delve into this conundrum and uncover a fascinating discovery that could shift the narrative.

Join us on Short Wave as host Regina G. Barber chats with biophysicist Nathalie Balaban. They explore the challenges and a breakthrough in bacterial research that might just be the key to turning the tide.

But here's where it gets controversial... Balaban's lab has made an intriguing observation about bacteria. And this is the part most people miss: it's not just about finding new antibiotics. It's about understanding the behavior of these tiny organisms and using that knowledge to our advantage.

So, are we ready to rethink our approach to fighting superbugs? This episode might just inspire a new perspective.

Check out our previous episodes on extreme bacteria in Yellowstone and the fascinating concept of the last universal common ancestor. And if you're curious about the science behind our medicines, drop us a line at shortwave@npr.org.

Support our work and enjoy sponsor-free episodes by signing up for Short Wave+ at plus.npr.org/shortwave.

This episode was produced by Berly McCoy, edited by Rebecca Ramirez, and fact-checked by Tyler Jones. Audio engineering by Jimmy Keeley.

A new way to fight antibiotic resistance (2026)
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